Past studies


Past studies



ACL Female Athlete

Study Name:

Two-year follow-up after ACL reconstruction in adolescent female athletes


Principal Investigator(s):

Brad Nelson MD

Co-Investigator(s):

Marc Tompkins MD

Diagnosis Being Studied:

The Anterior Cruciate Ligament (ACL) is one of the four major ligaments that make up your knee. A tear of the ACL may require reconstruction using another tendon or ligament to substitute the torn ligament. Tears of the ACL are increasing in incidence especially in the younger, active population as participation in more intense training and sports are beginning at an earlier age. As the demographic changes in youth sports and more females become involved, it is pertinent to evaluate if this population can be categorized with the general population or if there are differences between female outcomes and their male counterparts.

Innovation:

Evaluate the long-term outcomes of female athletes who have undergone an ACL reconstruction to determine the rate of return to sport and the re-rupture rate of the ACL graft.


ACL Long Term Follow-up

Study Name:

Long Term Follow Up of ACL Reconstructions of a Single Surgeon


Principal Investigator(s):

David Fischer MD

Diagnosis Being Studied:

The Anterior Cruciate Ligament (ACL) is one of the four major ligaments that make up the knee. A tear of the ACL may require reconstruction using another tendon or ligament to substitute the torn ligament. An ACL reconstruction is performed to stabilize the knee, restore function, and prevent additional damage to other structures in the knee. 

Innovation:

Evaluate the long-term outcomes of patients who have undergone an ACL reconstruction to determine return to sport/activity, graft health, knee function, knee osteoarthritis, and concomitant surgeries. 


ACL Neuromuscular Training

Study Name:

Long Term Effects of a 5 Week Neuromuscular Training Program on Lower Limb Symmetry Index Scores, and Outcomes Scores following Unilateral Anterior Cruciate Ligament Reconstruction


Principal Investigator(s):

Brad Nelson MD

Co-Investigator(s):

John Bottoms PT, DPT, OCS ; Adam Meierbachtol PT, DPT, SCS, ATC ; Eric Paur PT, DPT, SCS, ATC

Diagnosis Being Studied:

Neuromuscular training programs for the prevention and rehabilitation of major knee injuries have become increasingly popular due to the increased awareness of proper body kinematics and improvements in strength demonstrated by patients who choose to participate in these programs. While studies have demonstrated improvements in function following neuromuscular training programs, few if any studies have demonstrated the long-term (more than one year post-operatively) benefits on function and return to play.

Innovation:

Determine if a neuromuscular training program, specifically TRIA Lower Extremity Agility Program (TRIA L.E.A.P.), can be implemented as a post-operative ACL reconstruction tool to provide long-term benefits on lower limb symmetry index and outcome scores.


ACL Return to Function

Study Name:

Timeline of Return to Activities of Daily Living Following Anterior Cruciate Ligament Reconstruction


Principal Investigator(s):

Brad Nelson MD

Co-Investigator(s):

Joel Boyd MD ; David Fischer MD ; Alan Markman MD ; John Steubs MD ; Gary Fetzer MD ; Kirk Aadalen MD ; Marc Tompkins MD ; Devanshu Kansara, MD

Diagnosis Being Studied:

The Anterior Cruciate Ligament (ACL) is one of the four major ligaments that make up your knee. A tear of the ACL may require a procedure called ACL reconstruction. The ACL is reconstructed using another tendon or ligament to substitute the torn ligament.

Innovation:

Evaluating the short-term outcomes and return to activities of daily living following ACL reconstruction.


Activity Scale

Study Name:

Activity Scale Ease of Use, Reliability and Responsiveness in a US Population


Principal Investigator(s):

Marc Swiontkowski MD

Co-Investigator(s):

Julie Agel

Diagnosis Being Studied:

The Activity Scale instrument is a questionnaire designed to measure how injury/illness effects activities, specifically at how often and for how long the activity is participated in.

Innovation:

Determine the ease of use, reliability with re-testing, and responsiveness to change following an injury for the Activity Scale.


DeNovo Cartilage Treatment

Study Name:

A Stratified, Post-Market Study of DeNovo NT for Treatment of Femoral and Patellar Articular Cartilage Lesions of the Knee


Principal Investigator(s):

Brad Nelson MD

Co-Investigator(s):

Ross Paskoff MD ; Marc Tompkins MD ; Joel Boyd MD

Diagnosis Being Studied:

Articular cartilage injury of the knee is a major cause of disability in North America. Arthritis, trauma, and sports injury can lead to damaged cartilage surfaces causing pain, functional impairment, effusions, and in some cases, progressive knee joint degeneration. Damage to articular cartilage is a common problem that is often under-appreciated or masked by other concomitant knee injuries.

Innovation:

Evaluate the improvement in clinical outcomes for treatment of articular cartilage lesions of the knee using DeNovo NT, which is a FDA-approved, juvenile cartilaginous tissue graft.


Dupuytren’s Contracture

Study Name:

A Phase 3b open-label, historically-controlled study to assess the safety and efficacy of two concurrent injections of AA4500 in adult subjects with multiple Dupuytren's contractures with palpable cords.


Principal Investigator(s):

Jeffrey Husband MD

Diagnosis Being Studied:

In people with Dupuytren’s contracture, there is thickening of the skin and tissue in the palm of your hand that is not normal. Over time, this thickened tissue can form a cord in your palm. This causes one or more of your fingers to bend toward the palm, so you cannot straighten them. The study doctor and Auxilium Pharmaceuticals, Inc. are conducting a research study of a drug called AA4500 (collagenase clostridium histolyticum), the brand name of AA4500 in the US is Xiaflex. Xiaflex is a prescription medicine approved by the US Food and Drug Administration (FDA) to treat adults with Dupuytren’s contracture when a “cord” can be felt (a palpable cord).  Currently, Xiaflex is approved to be injected into one cord at a time and injections and finger extension procedures may be administered up to 3 times per cord at approximately every 4 weeks.

Innovation:

Assess the safety and efficacy of the administration of injections of AA4500 (Xiaflex) into the same hand with multiple Dupuytren’s contractures caused by palpable cords followed by a finger extension procedure.


Knee Osteoarthritis

Study Name:

Evaluating the Efficacy of Lateral Heel Wedges for Osteoarthritis of the Knee


Principal Investigator(s):

Marc Tompkins MD

Diagnosis Being Studied:

Knee osteoarthritis is a degenerative condition in which the cartilage that protects the knee joint wears down over a period of time. Given the prevalence of osteoarthritis of the knee and the general aging trends of the population, it is important to develop effective non-operative interventions to reduce pain and improve function in the adult population with osteoarthritis (OA) of the knee.

Innovation:

The purpose of this investigation is to document the acceptability and effectiveness of a shoe insert in a group of patients with significant osteoarthritis of the knee.


KOOS Normative

Study Name:

Use of the Knee Injury and Osteoarthritis Outcomes Survey (KOOS) in a Normal US Population


Principal Investigator(s):

Brad Nelson MD

Co-Investigator(s):

Robby Sikka MD

Diagnosis Being Studied:

The Knee Injury and Osteoarthritis Outcomes Survey (KOOS) is a questionnaire developed to measure symptoms, knee function as it relates to sport and recreation, pain, activities of daily living, and knee-related quality of life.

Innovation:

Determine baseline KOOS questionnaire scores in a US population who do not report knee pain.


Learner Letter

Study Name:

Influence of a Letter on Patient Opinion Regarding Residents and Students


Principal Investigator(s):

Co-Investigator(s):

Jonathan Braman MD ; Brad Nelson MD ; Marc Tompkins MD ; Jeffrey Macalena, MD

Diagnosis Being Studied:

Physicians at TRIA Orthopaedic Center have the privilege of providing training to residents and medical students throughout our clinic and surgery center. As part of this training, residents and medical students are involved in all aspect of patient care from consultations to surgery.

Innovation:

As educating future doctors is one of the important missions at TRIA, we are studying how our patients understand the role that students have in their care.


Sitemap

Connect & Find Us

Schedule an Appointment

Bloomington
8100 Northland Drive
Bloomington, MN 55431
952-831-8742

Get Directions

St. Paul
400 Wabasha Street
St. Paul, MN 55401
952-831-8742

Get Directions

Woodbury
155 Radio Drive
Woodbury, MN 55125
952-831-8742

Get Directions

Find Us

Maple Grove
9555 Upland Lane North
Maple Grove, MN 55369
952-806-5600

Get Directions

TRIA Physical Therapy and
Education Center
3800 American Blvd W.
Bloomington, MN 55431

Get Directions

TRIA Mailing List

If you are interested in receiving TRIA updates, sign up for our mailing list:
  • This field is for validation purposes and should be left unchanged.